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EI1 1418308-27-6 EI1 is a potent and selective EZH2 inhibitor with IC50 of 15 nM and 13 nM for EZH2 (WT) and EZH2 (Y641F), respectively.
Splitomicin 5690-03-9 Splitomicin is a selective NAD(+)-dependent histone deacetylase Sir2p inhibitor with IC50 of 60 μM, showing a higher activity in a cell-based assay.
TAI-1 1334921-03-7 TAI-1 is a potent and specific Hec1 inhibitor, which disrupts Hec1-Nek2 protein interaction.
SB273005 205678-31-5 SB273005 is a potent integrin inhibitor with Ki of 1.2 nM and 0.3 nM for αvβ3 receptor and αvβ5 receptor, respectively.
CH5138303 959763-06-5 CH5138303 is an orally available Hsp90 inhibitor with Kd of 0.48 nM.
ARQ 621 1095253-39-6 ARQ 621 is an allosteric, and selective Eg5 mitotic motor protein inhibitor. Phase 1.
Epothilone A 152044-53-6 Epothilone A is a Taxol-like microtubule-stabilizing agent with EC0.01 of 2 μM.
K-Ras(G12C) inhibitor 12 1469337-95-8 K-Ras(G12C) inhibitor 12 is an allosteric inhibitor of oncogenic K-Ras(G12C).
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