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Piboserod 152811-62-6 Piboserod (SB 207266) is a selective 5-HT(4) receptor antagonist.
YK-4-279 1037184-44-3 YK 4-279 is an inhibitor of RNA Helicase A (RHA) binding to the oncogenic transciption factor EWS-FLI1. YK-4-279 inhibits Ewing's sarcoma family tumor (ESFT) cell growth;
ITD-1 1099644-42-4 ITD-1 is an inducer of TGF_beta_ type II receptor degradation-1, is a potent and highly selective TGF_beta_ pathway inhibitor (IC50 = 0.85 uM).
SBE13 Hydrochloride 1052532-15-6 SBE13 hydrochloride is a potent and selective PLK1 with IC50 of 0.2 nM; no inhibition om Aurora A kinase, Plk2 and Plk3.
Trans-Tranilast 70806-55-2 Trans-Tranilast is an antiallergic drug, used to treat bronchial asthma, allergic rhinitis and atopic dermatitis.
AM281 202463-68-1 Cannabinoid antagonist AM 281 reduces mortality rate and neurologic dysfunction after cecal ligation and puncture in rats.
GHF-5074 749269-83-8 CHF5074 is a novel γ-secretase modulator, reduces Aβ42 and Aβ40 secretion, with an IC50 of 3.6 and 18.4 μM, respectively.
VER-50589 747413-08-7 VER-50589 is a potent HSP90 inhibitor with IC50 of 21 nM for HSP90β.
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