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详细介绍
| 品牌 | absin | 纯度 | Greater than 95% as determined by reduci |
|---|---|---|---|
| 货号 | abs04116 | 规格 | 10ug |
| 供货周期 | 现货 | 主要用途 | is produced by our Mammalian expression |
| 应用领域 | 化工,生物产业,农林牧渔,制药/生物制药,综合 |
Recombinant Human PRCP Protein(C-6His)
| 产品描述 | |
| 描述 | Recombinant Human Lysosomal Pro-X Carboxypeptidase is produced by our Mammalian expression system and the target gene encoding Leu22-His496 is expressed with a 6His tag at the C-terminus. |
| 别名 | PRCP蛋白;Lysosomal Pro-X Carboxypeptidase; Angiotensinase C; Lysosomal Carboxypeptidase C; Proline Carboxypeptidase; Prolylcarboxypeptidase; PRCP; PRCP; PCP |
| 种属 | Human |
| 来源 | Human Cells |
| 形态 | Supplied as a 0.2 μm filtered solution of 20mM NaAc-HAc,150mM NaCl,10%Glycerol,pH4.5. |
| 储存/保存方法 | Store at < -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles. |
| 性能 | |
| 序列 | LRPALRALGSLHLPTNPTSLPAVAKNYSVLYFQQKVDHFGFNTVKTFNQRYLVADKYWKKNGGSI LFYTGNEGDIIWFCNNTGFMWDVAEELKAMLVFAEHRYYGESLPFGDNSFKDSRHLNFLTSEQAL ADFAELIKHLKRTIPGAENQPVIAIGGSYGGMLAAWFRMKYPHMVVGALAASAPIWQFEDLVPCG VFMKIVTTDFRKSGPHCSESIHRSWDAINRLSNTGSGLQWLTGALHLCSPLTSQDIQ |
| 标签 | C-6His |
| 纯度 | Greater than 95% as determined by reducing SDS-PAGE. |
| 内毒素水平 | Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test. |
| 靶标 | |
| 背景说明 | Lysosomal Pro-X Carboxypeptidase (PRCP) belongs to the peptidase S28 family. PRCP is detected in many tissues, with highest levels observed in placenta, lung, and liver. It is also present in the heart, brain, pancreas, and kidney. PRCP exists as a homodimer. PRCP cleaves C-terminal amino acids linked to proline in peptides such as angiotensin II, III and des-Arg9-bradykinin. This cleavage occurs at acidic pH, but enzymatic activity is retained with some substrates at neutral pH. PRCP has been shown to be an activator of the cell matrix-associated prekallikrein. |
| Accession | P42785 |
| 研究领域 | |
| 研究领域 | CardiovascularBloodBlood Pressure regulation Proteolysis / UbiquitinProteolytic enzymesOther proteases |
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