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详细介绍
| 品牌 | absin | 纯度 | Greater than 95% as determined by reduci |
|---|---|---|---|
| 货号 | abs04117 | 规格 | 10ug |
| 供货周期 | 现货 | 主要用途 | is produced by our Mammalian expression |
| 应用领域 | 化工,生物产业,农林牧渔,制药/生物制药,综合 |
Recombinant Human Trappin-2 Protein(C-6His)
| 产品描述 | |
| 描述 | Recombinant Human Elafin is produced by our Mammalian expression system and the target gene encoding Ala23-Gln117 is expressed with a 6His tag at the C-terminus. |
| 别名 | Elafin蛋白；Trappin-2蛋白;Elafin; Elastase-Specific Inhibitor; ESI; Peptidase Inhibitor 3; PI-3; Protease inhibitor WAP3; Skin-Derived Antileukoproteinase; SKALP; WAP Four-Disulfide Core Domain Protein 14; PI3; WAP3; WFDC14 |
| 种属 | Human |
| 来源 | Human Cells |
| 形态 | Supplied as a 0.2 μm filtered solution of 20mM TrisHCl, 150mM NaCl, pH 7.5. |
| 储存/保存方法 | Store at < -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles. |
| 性能 | |
| 序列 | AVTGVPVKGQDTVKGRVPFNGQDPVKGQVSVKGQDKVKAQEPVKGPVSTKPGSCPIILIRCAMLN PPNRCLKDTDCPGIKKCCEGSCGMACFVPQVDHHHHHH |
| 标签 | C-6His |
| 纯度 | Greater than 95% as determined by reducing SDS-PAGE. |
| 内毒素水平 | Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test. |
| 靶标 | |
| 背景说明 | Elafin is a secreted protein. Elafin consists of two domains: the transglutaminase substrate domain (cementoin moiety) and the elastase inhibitor domain. The transglutaminase substrate domain serves as an anchor to localize Elafin covalently to specific sites on extracellular matrix proteins. It is shown that Elafin can be used as a biomarker for graft versus host disease of the skin. Elafin is expressed in the skin during wound healing through activation of the epidermal growth factor receptor. Elafin may prevent elastase-mediated tissue proteolysis. |
| Accession | P19957 |
| 研究领域 | |
| 研究领域 | CancerTumor biomarkersOther Proteolysis / UbiquitinProtease inhibitorsOther protease inhibitors ImmunologyImmune System DiseasesAutoimmune ImmunologyInnate ImmunityMacrophage / Inflamm. MicrobiologyAntimicrobialAntibiotic |
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