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首页 > 产品中心 > 细胞生物学 > 重组蛋白 > abs02005Recombinant Human TIM-3 Protein

Recombinant Human TIM-3 Protein

简要描述:Recombinant human TIM3 protein aa1-201 was produced in mammalian cells with C-terminal His-DYK tag. The theoretical molecular weight of recombinant TIM3 is 22.1 kDa.

  • 产品型号:abs02005
  • 厂商性质:生产厂家
  • 更新时间:2024-03-03
  • 访  问  量:1202

详细介绍

品牌absinCAS-
分子式-纯度-
分子量-货号abs02005
规格10ug;100ug供货周期现货
主要用途-应用领域生物产业

描述:

Recombinant human TIM3 protein aa1-201 was produced in mammalian cells with C-terminal His-DYK tag. The theoretical molecular weight of recombinant TIM3 is 22.1 kDa. Purified TIM3 protein is between the position of 43-26 kDa on SDS-PAGE gel under reduced condition.
TIM3 protein is purified by proprietary chromatographic techniques.


Entrez Gene summary for TIM3:

The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance.


UniProtKB/Swiss-Prot: Q8TDQ0 (HAVR2_HUMAN)

Function: Cell surface receptor implicated in modulating innate and adaptive immune responses. Generally accepted to have an inhibiting function.


别名:

TIM-3蛋白;T-cell immunoglobulin and mucin domain-containing protein 3 / TIMD-3 T-cell immunoglobulin mucin receptor 3 / TIM-3 T-cell membrane protein 3


来源:

Mammalian cells


形态:

Protein is supplied in 20 mM Tris,150 mM NaCl, 10% Glycerol, pH 7.5。


保存方法:

Clear solution, frozen.Store at -70°C. At first use, aliquot and store at -70°C to avoid multiple freeze-thaws.


Accession:

NP_116171.3

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