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PD184352 (CI-1040) 212631-79-3 PD184352 (CI-1040) is an ATP non-competitive MEK1/2 inhibitor with IC50 of 17 nM in cell-based assays, 100-fold more selective for MEK1/2 than MEK5. Phase 2.
IC261 186611-52-9 IC261 is a novel inhibitor of CK1, triggers the mitotic checkpoint control. The IC50 of IC261 for CK1 was 16 μM and for Cdk5 is 4.5 mM.
HMN-214 173529-46-9 HMN-214(IVX214) is a potent PLK1 inhibitor an average IC50 of 0.12 μM.
LY 303511 154447-38-8 LY303511, an inactive analogue of LY294002, is a mTOR inhibitor that did not inhibit PI3-K.
PHOB 1429651-50-2 HPOB is a potent, selective HDAC6 inhibitor with IC50 of 56 nM, 30-fold selectivity over other HDACs.
爱必信(absin)的目标是为科学研究者提供快速、简单的研究工具,推进创新和研发进程。
BIX02189 1094614-85-3;1265916-41-3 BIX02189 is a selective inhibitor of MEK5 with IC50 of 1.5 nM, also inhibits ERK5 catalytic activity with IC50 of 59 nM in cell-free assays
Nedaplatin 95734-82-0 Nedaplatin (NSC 375101D) is a derivative of cisplatin and DNA damage agent.