详细介绍
| 品牌 | absin | 纯度 | Greater than 95% as determined by reduci |
|---|---|---|---|
| 货号 | abs04115 | 规格 | 10ug |
| 供货周期 | 现货 | 主要用途 | is produced by our Mammalian expression |
| 应用领域 | 化工,生物产业,农林牧渔,制药/生物制药,综合 |
Recombinant Human NEU-1 Protein(C-6His)
| 产品描述 | |
| 描述 | Recombinant Human Sialidase-1 is produced by our Mammalian expression system and the target gene encoding Glu48-Leu415 is expressed with a 6His tag at the C-terminus. |
| 别名 | Sialidase-1蛋白;NEU-1蛋白;Sialidase-1; Acetylneuraminyl Hydrolase; G9 Sialidase; Lysosomal Sialidase; N-Acetyl-Alpha-Neuraminidase 1; NEU1; NANH |
| 种属 | Human |
| 来源 | Human Cells |
| 形态 | Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl,10% Glycerol, pH 7.4. |
| 储存/保存方法 | Store at < -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles. |
| 性能 | |
| 序列 | ENDFGLVQPLVTMEQLLWVSGRQIGSVDTFRIPLITATPRGTLLAFAEARKMSSSDEGAKFIALR RSMDQGSTWSPTAFIVNDGDVPDGLNLGAVVSDVETGVVFLFYSLCAHKAGCQVASTMLVWSKDD GVSWSTPRNLSLDIGTEVFAPGPGSGIQKQREPRKGRLIVCGHGTLERDGVFCLLSDDHGASWRY GSGVSGIPYGQPKQENDFNPDECQPYELPDGSVVINARNQNNYHCHCRIVLRSYDAC |
| 标签 | C-6His |
| 纯度 | Greater than 95% as determined by reducing SDS-PAGE. |
| 内毒素水平 | Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test. |
| 靶标 | |
| 背景说明 | Sialidase-1 belongs to the N-acetyl-a neuraminidase family. Sialidase-1 is expressed in many tissues; it is highly expressed in the pancreas, and weakly expressed in the brain. Sialidase-1 is a lysosomal enzyme, which cleaves terminal sialic acid residues from substrates such as glycoproteins and glycolipids. Deficiencies in the human enzyme Sialidase-1 leads to sialidosis, a rare lysosomal storage disease. Sialidase-1 has been shown to interact with Cathepsin A (protective protein), β-galactosidase and N-acetylgalactosamine-6-sulfate sulfatase in a multienzyme complex. |
| Accession | Q99519 |
| 研究领域 | |
| 研究领域 | MetabolismPathways and ProcessesMetabolic signaling pathwaysAmino acid metabolism MetabolismPathways and ProcessesMetabolic signaling pathwaysEnergy transfer pathwaysEnergy Metabolism NeuroscienceProcesses Signal TransductionMetabolismAmino Acids Signal TransductionMetabolismEnergy Metabolism |
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