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详细介绍
| 品牌 | absin | 纯度 | Greater than 95% as determined by reduci |
|---|---|---|---|
| 货号 | 10ug | 规格 | 10ug |
| 供货周期 | 现货 | 主要用途 | is produced by our Mammalian expression |
| 应用领域 | 化工,生物产业,农林牧渔,制药/生物制药,综合 |
Recombinant Human PRTN3 Protein(C-6His)
| 产品描述 | |
| 描述 | Recombinant Human Proteinase 3 is produced by our Mammalian expression system and the target gene encoding Ala26-Arg249 is expressed with a 6His tag at the C-terminus. |
| 别名 | ase 3蛋白；PRTN3蛋白；Myeloblastin蛋白;Myeloblastin; AGP7; C-ANCA Antigen; Leukocyte Proteinase 3; PR-3; PR3; Neutrophil Proteinase 4; NP-4; P29; Wegener Autoantigen; PRTN3; MBN |
| 种属 | Human |
| 来源 | Human Cells |
| 形态 | Supplied as a 0.2 μm filtered solution of 10mM TrisHCl, 150mM NaCl, 10% Glycerol, pH 8.0. |
| 储存/保存方法 | Store at < -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles. |
| 性能 | |
| 序列 | AEIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGAHNV RTQEPTQHFSVAQVFLNNYDAENKLNDVLLIQLSSPANLSASVATVQLPQDQPVPHGTQCLAM GWGRVGAHDPPAQVLQELNVTVVTFFCRPHNICTFVPRRKAGICFGDSGGPLICDGIIQGIDSFV IWGCATRLFPDFFTRVALYVDWIRSTLRRVDHHHHHH |
| 标签 | C-6His |
| 纯度 | Greater than 95% as determined by reducing SDS-PAGE. |
| 内毒素水平 | Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test. |
| 靶标 | |
| 背景说明 | Proteinase-3 is a neutral serine proteinase that belongs to the peptidase S1 family and Elastase subfamily. It contains one peptidase S1 domain and it is expressed mainly in neutrophil granulocytes. The primary function of Proteinase-3 is thought to be degradation of extracellular proteins at sites of inflammation, but excessive or prolonged proteolytic activity may cause harmful effects in the body. It is the epitope of anti-neutrophil cytoplasmic antibodies (ANCAs) of the cANCA (cytoplasmic subtype) class, a type of antibody frequently found in the disease Wegener's granulomatosis. |
| Accession | P24158 |
| 研究领域 | |
| 研究领域 | Signal TransductionCytoskeleton / ECMBasal Lamina Signal TransductionCytoskeleton / ECMExtracellular MatrixOther EnzymesECM Enzymes Signal TransductionCytoskeleton / ECMExtracellular MatrixECM ProteinsCollagen |
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