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详细介绍
| 品牌 | absin | 纯度 | Greater than 95% as determined by reduci |
|---|---|---|---|
| 货号 | abs04106 | 规格 | 10ug |
| 供货周期 | 现货 | 主要用途 | is produced by our Mammalian expression |
| 应用领域 | 化工,生物产业,农林牧渔,制药/生物制药,综合 |
Recombinant Human MMP-3 Protein(C-6His)
| 产品描述 | |
| 描述 | Recombinant Human Matrix Metalloproteinase-3 is produced by our Mammalian expression system and the target gene encoding Tyr18-Cys477 is expressed with a 6His tag at the C-terminus. |
| 别名 | Matrix Metalloase-3蛋白；MMP-3蛋白;Stromelysin-1; SL-1; Matrix metalloproteinase-3; MMP-3; Transin-1; MMP3; STMY1 |
| 种属 | Human |
| 来源 | Human Cells |
| 形态 | Supplied as a 0.2 μm filtered solution of 20mM TrisHCl, 150mM NaCl, 0.05% Brij35, 10% Glycerol, pH 7.5. |
| 储存/保存方法 | Store at < -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles. |
| 性能 | |
| 序列 | YPLDGAARGEDTSMNLVQKYLENYYDLEKDVKQFVRRKDSGPVVKKIREMQKFLGLEVTGKLDSD TLEVMRKPRCGVPDVGHFRTFPGIPKWRKTHLTYRIVNYTPDLPKDAVDSAVEKALKVWEEVTPL TFSRLYEGEADIMISFAVREHGDFYPFDGPGNVLAHAYAPGPGINGDAHFDDDEQWTKDTTGTNL FLVAAHEIGHSLGLFHSANTEALMYPLYHSLTDLTRFRLSQDDINGIQSLYGPPPDS |
| 标签 | C-6His |
| 纯度 | Greater than 95% as determined by reducing SDS-PAGE. |
| 内毒素水平 | Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test. |
| 靶标 | |
| 背景说明 | MMP3 is a member of the matrix metalloproteinase (MMP) family whose members are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, tissue remodeling, and disease processes including arthritis and metastasis. The MMP-3 enzyme degrades collagen types II, III, IV, IX, and X, proteoglycans, fibronectin, laminin, and elastin. In addition, MMP-3 can also activate other MMPs such as MMP-1, MMP-7, and MMP-9, rendering MMP-3 crucial in connective tissue remodeling.[3] The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation. |
| Accession | P08254 |
| 研究领域 | |
| 研究领域 | CancerInvasion/microenvironmentAngiogenesisECM enzymesMMPs CancerInvasion/microenvironmentECMExtracellular matrixMMPs CancerTumor biomarkersEnzymesMMPs CardiovascularAtherosclerosisThrombosisOther Proteolysis / UbiquitinProteolytic enzymesMetalloproteaseMMPs NeuroscienceDiseases NeuroscienceProcesses Signal TransductionCytoskeleton / ECMExtracellular MatrixMMPECM Enzymes CardiovascularAngiogenesisAdhesion / ECMMatrix MetalloproteinasesMMP |
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