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详细介绍
| 品牌 | absin | 纯度 | Greater than 95% as determined by reduci |
|---|---|---|---|
| 货号 | abs04086 | 规格 | 10ug |
| 供货周期 | 现货 | 主要用途 | Supplied as a 0.2 μm filtered solution |
| 应用领域 | 化工,生物产业,农林牧渔,制药/生物制药,综合 |
Recombinant Human IL-1β Protein
| 概述 | |
| 描述 | Recombinant Human Interleukin-1 beta is produced by our E.coli expression system and the target gene encoding Ala117-Ser269 is expressed. |
| 别名 | Interleukin-1β蛋白；IL-1β蛋白;Interleukin-1 beta; Catabolin; IL1F2; IL1B. |
| 种属 | Human |
| 来源 | Escherichia coli. |
| 形态 | Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 7.5. |
| 性能 | |
| 序列 | MAPVRSLNCTLRDSQKSLVMSGPYELKALHLQGQDMEQVVFSMSFVQGEESNDKIPVALGLKE KNLYLSCVLKDDKPTLQLESVDPKNYPKKKMEKRFVFNKIEINNKLEFESAQFPNWYISTSQAEN MPVFLGGTKGGQDITDFTMQFVSS |
| 标签 | No Tag |
| 纯度 | Greater than 95% as determined by reducing SDS-PAGE. |
| 内毒素水平 | Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test. |
| 活性 | Measured by its ability to induce NF-kB signaling in 293-IL1 Res cells. The ED50 for this effect is 20-100 pg/ml.Purity: Greater than 95% as determined by reducing SDS-PAGE. Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test. |
| 溶解方法 | Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 储存/保存方法 | Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
| 靶标 | |
| 背景说明 | IL1B belongs to the IL-1 family. Interleukin 1 (IL-1) is a family of polypeptide cytokines consisting of two agonists, IL-1 alpha (IL-1F1) and IL-1 beta (IL-1F2) encoded by two distinct genes and perform identical biological functions. IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response. It is identified as endogenous pyrogens, and is reported to stimulate the release of prostaglandin and collagenase from synovial cells. |
| Accession | P01584 |
| 研究领域 | |
| 研究领域 | CardiovascularAtherosclerosisVascular InflammationInflammatory mediators ImmunologyInnate ImmunityCytokinesInterleukins MetabolismTypes of diseaseObesity NeuroscienceProcesses MicrobiologyOrganismVirusRNA VirusssRNA positive strand virusSARS Coronavirus |
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