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首页 > 产品中心 > 细胞生物学 > 重组蛋白 > abs04089Recombinant Human IL-17RA Protein(C-Fc)

Recombinant Human IL-17RA Protein(C-Fc)

简要描述:Recombinant Human IL-17RA Protein(C-Fc)
is produced by our Mammalian expression system and the target gene encoding Leu33-Trp320 is expressed with a Fc tag at the C-terminus.

  • 产品型号:abs04089
  • 厂商性质:生产厂家
  • 更新时间:2026-04-07
  • 访  问  量:1400

详细介绍

品牌absin纯度Greater than 95% as determined by reduci
货号abs04089规格10ug
供货周期现货主要用途is produced by our Mammalian expression
应用领域化工,生物产业,农林牧渔,制药/生物制药,综合

Recombinant Human IL-17RA Protein(C-Fc)

产品描述
描述
Recombinant Human Interleukin-17 receptor A is produced by our Mammalian expression system and the target gene encoding Leu33-Trp320 is expressed with a Fc tag at the C-terminus.
别名
IL-17 Receptor A蛋白;IL-17RA蛋白;CD217蛋白;Interleukin-17 receptor A; IL-17 receptor A; IL-17RA; CDw217; CD_antigen; CD217; IL17RA; IL17R
种属
Human
来源
Human Cells
形态
Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4.
储存/保存方法
Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
性能
序列
LRLLDHRALVCSQPGLNCTVKNSTCLDDSWIHPRNLTPSSPKDLQIQLHFAHTQQGDLFPVAHIE WTLQTDASILYLEGAELSVLQLNTNERLCVRFEFLSKLRHHHRRWRFTFSHFVVDPDQEYEVTVH HLPKPIPDGDPNHQSKNFLVPDCEHARMKVTTPCMSSGSLWDPNITVETLEAHQLRVSFTLWNES THYQILLTSFPHMENHSCFEHMHHIPAPRPEEFHQRSNVTLTLRNLKGCCRHQVQIQ
标签
C-Fc
纯度
Greater than 95% as determined by reducing SDS-PAGE.
内毒素水平
Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test.
活性
Measured by its ability to inhibit IL-17-induced IL-6 secretion by NIH-3T3 mouse embryonic fibroblast cells.The ED50 for this effect is 20-100 ng/ml.
溶解方法
Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
靶标
背景说明
Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The transmembrane protein encoded by this gene (interleukin 17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure.
Accession
Q96F46
研究领域
研究领域
ImmunologyInnate ImmunityMacrophage / Inflamm.
ImmunologyInnate ImmunityCytokinesInterleukins
Recombinant Human IL-17RA Protein(C-Fc)温馨提示:本产品仅作科研实验使用,不支持临床等研究

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