SP600125是一种广谱JNK抑制剂，作用于JNK1，JNK2和JNK3，无细胞试验中IC50分别为40nM，40nM和90nM，比作用于MKK4选择性高10倍，比作用于MKK3，MKK6，PKB，和PKCα选择性高25倍，比作用于ERK2，p38，Chk1，EGFR等选择性高100倍。

Quisinostat (JNJ-26481585) 2HCl 875320-31-3 Quisinostat (JNJ-26481585) 2HCl is a novel second-generation HDAC inhibitor with highest potency for HDAC1 with IC50 of 0.11 nM in a cell-free assay

LY-411575 209984-57-6 LY411575 is a potent γ-secretase inhibitor with IC50 of 0.078 nM/0.082 nM (membrane/cell-based), also inhibits Notch clevage with withIC50 of 0.39 nM.

GO-6983 is a pan-PKC inhibitor against for PKCα, PKCβ, PKCγ and PKCδ with IC50 of 7 nM, 7 nM, 6 nM and 10 nM, respectively; less potent to PKCζ and inactive to PKCμ.

TWS119 601514-19-6 TWS119 is a GSK-3β inhibitor with IC50 of 30 nM.

Anacetrapib 875446-37-0 Anacetrapib (MK0859) is a potent, selective, reversible rhCETP and mutant CETP(C13S) inhibitor with IC50 of 7.9 nM and 11.8 nM,

VE-821 1232410-49-9 VE-821 is a potent and selective ATP competitive inhibitor of ATR with Ki and IC50 of 13 nM and 26 nM, respectively.

Ixazomib Citrate 1201902-80-8 MLN-9708 is a proteasome inhibitor, which inhibits the activity of the proteasome, blocking the targeted proteolysis normally performed by the proteasome.