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SD-208 627536-09-8 SD-208 is a selective TGF-βRI (ALK5) inhibitor with IC50 of 48 nM, 100-fold selectivity over TGF-βRII.
Neomycin Sulphate B 4146-30-9 Neomycin belongs to aminoglycoside class of antibiotics that contain two or more aminosugars connected by glycosidic bonds.
Eniporide 176644-21-6 eniporide is a Na(+)/H(+) exchange inhibitor.
APD 668 832714-46-2 APD668 is a potent GPR119 agonist with EC50 of 2.7 nM and 33 nM for hGPR119 and ratGPR119 respectively.
AF 353 865305-30-2 AF-353 is a novel, potent and orally bioavailable P2X3/P2X2/3 receptor antagonist, inhibits human and rat P2X3 (pIC50= 8.0).
ELN 441958 913064-47-8 ELN-441958 is a potent, neutral antagonist of B1 receptor, inhibits the binding of the B1 agonist ligand [3H]DAKD to IMR-90 cells with Ki of 0.26 nM.
PI3065 955977-50-1 PI-3065 is a novel potent and selective PI3K p110δ inhibitor with IC50 of 15 nM; exhibits 100 fold selectivity against p110α, p110β, p110γ, DNA-PK and mTOR.
CDK4-IN-1 1256963-02-6 CDK4 inhibitor is a novel and specific CDK4/Cyclin D1 inhibitor with an IC50 of 10 nM; 1500 and 500 fold than CDK1/Cyclin B (IC5015 uM)
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