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Regadenoson 313348-27-5 Regadenoson is an adenosine derivative and selective A2A adenosine receptor agonist with coronary vasodilating activity.
PIK-75 372196-67-3 PIK-75, a DNA-PK and PI3K inhibitor, suppresses DNA-PK(IC50=2 nM), p110α(IC50=5.8 nM) and p110γ(IC50=76 nM).
Fruquintinib 1194506-26-7 Fruquintinib (HMPL-013) is a small molecule vascular endothelial growth factor receptors inhibitor.
CEP37440 1391712-60-9 CEP-37440 is a novel potent and selective Dual FAK/ALK inhibitor with IC50 s of 2.3 nM (FAK) and 120 nM(ALK cellular IC50 in 75% human plasma).
MI-2 (Menin-MLL Inhibitor) 1271738-62-5 MI-2 (Menin-MLL Inhibitor) is a potent menin-MLL interaction inhibitor with IC50 of 446 nM.
HA130 1229652-21-4 HA130 is a selective ATX (autotaxin) inhibitor with IC50 of 28 nM.
KRCA-0008 1472795-20-2 KRCA-0008 is a potent and selective ALK/Ack1 inhibitor with IC50 of 12 nM/4 nM for ALK and Ack1 respectively; displays drug-like properties without hERG liability.
Exherin (ADH-1) 229971-81-7 Exherin (ADH-1) is a small, cyclic pentapeptide vascular-targeting agent with potential antineoplastic and antiangiogenic activities;
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