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Bortezomib 179324-69-7 Bortezomib is a potent 20S proteasome inhibitor with Ki of 0.6 nM.
BIBF 1120 esylate 656247-18-6 BIBF 1120 esylate是一种有效的 VEGFR1/2/3,FGFR1/2/3 和 PDGFRα/β 三重抑制剂,IC50 值分别为 34 nM/13 nM/13 nM,69 nM/37 nM/108 nM 和 59 nM/65 nM。
BAY11-7085 196309-76-9 BAY 11-7085 is an irreversible inhibitor of TNFα-induced IκBα phosphorylation with IC50 of 10 μM.
AZD-9291 1421373-65-0 AZD-9291 is a potent and selective mutated forms EGFR inhibitor(Exon 19 deletion EGFR IC50=12.92 nM, L858R/T790M EGFR IC50= 11.44 nM, wild type EGFR IC50= 493.8 nM).
YN968D1 1218779-75-9 Apatini (YN968D1) is an orally bioavailable, selective VEGFR2 inhibitor with IC50 of 1 nM.
AHU-377 hemicalcium salt 1369773-39-6 AHU-377 is an inhibitor of neprilysin with IC50 value of 5 nM.
AG 490 133550-30-8 AG-490 (Tyrphostin B42)是一种EGFR抑制剂,在无细胞试验中IC50为0.1μM,作用于EGFR比作用于ErbB2选择性高135倍,对JAK2也有抑制作用,对Lck,Lyn,Btk,Syk和Src没有抑制活性。
Afatinib 439081-18-2 BIBW2992 (Afatinib, Tomtovok, Tovok) irreversibly inhibits EGFR/HER2 including EGFRwt, EGFRL858R, EGFRL858R/T790M and HER2 with IC50 of 0.5 nM, 0.4 nM, 10 nM and 14 nM, respective