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PTC-209 HBr 1217022-63-3 PTC-209 HBr is the hydrobromide salt of PTC-209, which is a potent and selective BMI-1 inhibitor with IC50 of 0.5 μM, and results in irreversible reduction of cancer-initiatin
SU9516 377090-84-1 SU 9516 is a 3-substituted indolinone CDK inhibitor with IC50 of 22 nM, 40 nM, and 200 nM for CDK2, CDK1, and CDK4, respectively.
Salirasib 162520-00-5 Salirasib is a potent competitive prenylated protein methyltransferase (PPMTase) inhibitor with Ki of 2.6 μM, which inhibits Ras methylation. Phase 2.
S-Ruxolitinib 941685-37-6 S-Ruxolitinib is the chirality of INCB018424, which is the first potent, selective, JAK1/2 inhibitor to enter the clinic with IC50 of 3.3 nM/2.8 nM
YH239-EE 1364488-67-4 YH239-EE, the ethyl ester of YH239, is a potent p53-MDM2 antagonist and an apoptosis inducer.
CX-6258 hydrochloride 1353859-00-3 CX-6258 hydrochloride is a potent, orally efficacious pan-Pim kinase inhibitor with IC50 of 5 nM, 25 nM and 16 nM for Pim1, Pim2, and Pim3, respectively.
SB-334867 792173-99-0 SB-334867 is a selective orexin-1 (OX1) receptor antagonist.
Remodelin hydrobromide 1622921-15-6 Remodelin is a potent acetyl-transferase NAT10 inhibitor.
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