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| 品牌 | absin | CAS | 25655-41-8 |
|---|---|---|---|
| 分子式 | C6H9I2NO | 纯度 | ＞98% |
| 分子量 | 364.95 | 货号 | abs47028237 |
| 规格 | 10mg | 供货周期 | 现货 |
| 主要用途 | used as topical antiseptic | 应用领域 | 化工,生物产业,农林牧渔,制药/生物制药,综合 |
Povidone-iodine (PVP-I) 25655-41-8
| 产品描述 | |
| 描述 | Povidone-iodine is an iodinated polyvinyl polymer used as topical antiseptic in surgery and for skin and mucous membrane infections, also as aerosol. The iodine may be radiolabeled for research purposes. |
| 纯度 | ＞98% |
| 储存/保存方法 | Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution. |
| 基本信息 | |
| 别名 | 聚wei酮碘；聚乙烯吡咯烷酮碘络合物；iodopovidone |
| 外观 | 黄棕色至红棕色无定形粉末 |
| 可溶性/溶解性 | DMSO : 27 mg/mL Ethanol : 27 mg/mL Water : 26 mg/mL |
| 生物活性 | |
| In vitro(体外研究) | Exposure to PVP-I, of which concentrations are even lower than those used clinically, causes toxicity in epithelial cells. |
| In vivo(体内研究) | Povidone-iodine is a broad spectrum antiseptic for topical application in the treatment and prevention of infection in wounds, using the antiseptic properties of iodine. A study investigating its use in defective tissue in neural structures reveals that Myelin changes are absent or minimal in all cases of the control group but are present as markedly increased myelin degeneration in nearly all cases in the PVP-I group. Axonal degeneration and hypoxic neuronal damage are absent in the control group, whereas they are marked in half of the PVP-I group. No statistically significant differences are established in Schwann cell proliferation, venous congestion, and lymphocytic proliferation between the two groups. |
| 参考文献 | |
| 参考文献 |
| 研究领域 | |
| 研究领域 | Drug DiscoverySmall Molecule DrugLead Compound Discovery |
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