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| 品牌 | absin | CAS | 183204-72-0 |
|---|---|---|---|
| 分子式 | C9H12Cl2N4O2 | 纯度 | 98% |
| 分子量 | 279.12 | 货号 | abs47028013 |
| 规格 | 5mg | 供货周期 | 现货 |
| 主要用途 | is a thymidine phosphorylase inhibitor | 应用领域 | 化工,生物产业,农林牧渔,制药/生物制药,综合 |
Tipiracil HCl 183204-72-0
| 产品描述 | |
| 描述 | Tipiralacil, also known as TPI, is a thymidine phosphorylase inhibitor (TPI). Tipiracil is one of the active components in TAS-102, which is an anticancer drug candidate currently in clinical trials |
| 纯度 | 98% |
| 储存/保存方法 | Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution. |
| 基本信息 | |
| 可溶性/溶解性 | 10 mM in DMSO |
| 生物活性 | |
| 靶点 | Nucleoside Antimetabolite_Analog |
| In vitro(体外研究) | Tipiracil has antiangiogenic effect, and inhibits proliferation of endothelial cells. Tipiracil is a potent inhibitor of thymidine phosphorylase, which is the enzyme that degrades FTD. |
| In vivo(体内研究) | |
| 参考文献 | |
| 参考文献 |
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| 研究领域 | |
| 研究领域 | EpigeneticsDNA / RNADNA SynthesisOther MetabolismPathways and ProcessesMetabolic signaling pathwaysNucleotide metabolismPurine and pyrimidine synthesis Drug DiscoverySmall Molecule DrugLead Compound Discovery |
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