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氯谷胺;107097-80-3

简要描述:爱必信(absin)的目标是为科学研究者提供快速、简单的研究工具,推进创新和研发进程。

  • 产品型号:abs817481
  • 厂商性质:生产厂家
  • 更新时间:2024-01-30
  • 访  问  量:294

详细介绍

品牌absinCAS107097-80-3
货号abs817481规格2mg;5mg;10mg;50mg
供货周期现货应用领域生物产业,农业,综合
产品描述
描述
Loxiglumide is CCK receptor antagonist. Cholecystokinin receptors or CCK receptors are a group of G-protein coupled receptors which bind the peptide hormones cholecystokinin (CCK) or gastrin.
纯度
98%
储存/保存方法
Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution.
基本信息
别名
氯谷胺;CR-1505
外观
white to beige powder
可溶性/溶解性
DMSO : ≥ 100 mg/mL (216.74 mM)
生物活性
靶点
Cholecystokinin Receptor
In vivo(体内研究)
The effects of pancreatic rest by oral administration of CCK-1 receptor antagonist Loxiglumide and pancreas stimulation are investigated via endogenous CCK release induced by po protease inhibitor camostat on the recovery of pancreatic secretory function, and biochemical and histological changes of the pancreas after acute hemorrhagic pancreatitis. Oral administration of CCK-1 receptor antagonist Loxiglumide with a dose of 50 mg/kg body weight inhibits pancreatic exocrine secretion for more than 12 h. Thus, every 12-h administration of Loxiglumide might have completely blocks the effect of endogenously released CCK on the pancreas (pancreatic rest).


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爱必信(上海)生物科技有限公司
地址:上海市浦东新区新浩路58号申江科创园18栋
邮箱:info@absin.cn
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