Wiskostatin 253449-04-6

简要描述：Wiskostatin 253449-04-6
Wiskott-Aldrich syndrome protein (WASP) and WAVE stimulate actin-related protein (Arp)2/3-mediated actin polymerization

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详细介绍

品牌	absin	CAS	253449-04-6
分子式	C17H18Br2N2O	纯度	98%
分子量	426.15	货号	abs47027924
规格	1mg	供货周期	现货
主要用途	is a recently described chemical inhibit	应用领域	化工,生物产业,农林牧渔,制药/生物制药,综合

Wiskostatin 253449-04-6

产品描述
描述	Wiskott-Aldrich syndrome protein (WASP) and WAVE stimulate actin-related protein (Arp)2/3-mediated actin polymerization, leading to diverse downstream effects, including the formation and remodeling of cell surface protrusions, modulation of cell migration, and intracytoplasmic propulsion of organelles and pathogens. Selective inhibitors of individual Arp2/3 activators would enable more exact dissection of WASP- and WAVE-dependent cellular pathways and are potential therapeutic targets for viral pathogenesis. Wiskostatin is a recently described chemical inhibitor that selectively inhibits neuronal WASP (N-WASP)-mediated actin polymerization in vitro.
纯度	98%
储存/保存方法	Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
基本信息
别名	1-(3,6-dibromocarbazol-9-yl)-3-(dimethylamino)propan-2-ol
外观	white to beige powder
可溶性/溶解性	10 mM in DMSO
参考文献
参考文献	1. Guerriero CJ, Weisz OA. Am J Physiol Cell Physiol. 2007 Apr;292(4):C1562-6. 2. Bompard G, et al. BMC Cell Biol. 2008 Jul 30;9:42.

研究领域
研究领域	Neuroscience Drug DiscoverySmall Molecule DrugLead Compound Discovery

Wiskostatin 253449-04-6温馨提示：本产品仅作科研实验使用，不支持临床等研究

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