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| 品牌 | absin | CAS | 62-51-1 |
|---|---|---|---|
| 分子式 | C8H18ClNO2 | 纯度 | ＞98% |
| 分子量 | 195.69 | 货号 | abs47027818 |
| 规格 | 25mg | 供货周期 | 现货 |
| 主要用途 | used as a parasympathomimetic bronchocon | 应用领域 | 化工,生物产业,农林牧渔,制药/生物制药,综合 |
Methacholine Chloride 62-51-1
| 产品描述 | |
| 描述 | Methacholine chloride is a quaternary ammonium parasympathomimetic agent with the muscarinic actions of ACETYLCHOLINE. It is hydrolyzed by ACETYLCHOLINESTERASE at a considerably slower rate than ACETYLCHOLINE and is more resistant to hydrolysis by nonspecific CHOLINESTERASES so that its actions are more prolonged. It is used as a parasympathomimetic bronchoconstrictor agent and as a diagnostic aid for bronchial asthma. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1116) |
| 纯度 | ＞98% |
| 储存/保存方法 | Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution. |
| 基本信息 | |
| 别名 | 醋甲dan碱；氯化乙酰甲dan碱；Acetyl-β-methylcholine chloride |
| 外观 | White powder |
| 可溶性/溶解性 | DMSO : 42mg/mL |
| 生物活性 | |
| 靶点 | muscarinic receptor |
| In vitro(体外研究) | Methacholine induced modest effects on basal interleukin (IL)-8 and -6 secretion, whereas the secretion of RANTES, eotaxin, vascular endothelial growth factor-A and monocyte chemoattractant protein-1 was not affected. |
| 研究领域 | |
| 研究领域 | Drug DiscoverySmall Molecule DrugLead Compound Discovery |
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