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| 品牌 | absin | CAS | 68-35-9 |
|---|---|---|---|
| 分子式 | C10H10N4O2S | 纯度 | 99% |
| 分子量 | 250.28 | 货号 | abs47027397 |
| 规格 | 200mg | 供货周期 | 现货 |
| 主要用途 | used to treat urinary tract infections | 应用领域 | 化工,生物产业,农林牧渔,制药/生物制药,综合 |
Sulfadiazine 68-35-9
| 产品描述 | |
| 描述 | Sulfadiazine is a sulfonamide antibiotic. It eliminates bacteria that cause infections by stopping the production of folic acid inside the bacterial cell, and is commonly used to treat urinary tract infections (UTIs). In combination, sulfadiazine and pyrimethamine, can be used to treat toxoplasmosis, a disease caused by Toxoplasma gondii. |
| 纯度 | 99% |
| 储存/保存方法 | Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution. |
| 基本信息 | |
| 别名 | 磺胺mi啶 |
| 外观 | white powder |
| 可溶性/溶解性 | DMSO : 47 mg/mL (187.8 mM) |
| 生物活性 | |
| In vivo(体内研究) | In this study, the effectiveness of Sulfadiazine and Pyrimetamine for the treatment of mice during acute infection with different atypical T. gondii strains was evaluated. Swiss mice were infected with seven T. gondii strainsl. The infected mice were treated with 10-640 mg/kg per day of Sulfadiazine, 3-200 mg/kg per day of Pyrimetamine, or a combination of both drugs with a lower dosage. A descriptive analysis was used to assess the association between susceptibility to Sulfadiazine and/or Pyrimetamine and the genotype. The TgCTBr4 and TgCTBr17 strains (genotype 108) presented lower susceptibility to Sulfadiazine or Pyrimetamine treatment. The TgCTBr1 and TgCTBr25 strains (genotype 206) presented similar susceptibility to PYR but not Sulfadiazine treatment. The TgCTBr9 strain (genotype 11) was the only strain with high susceptibility to treatment with both drugs. |
| 参考文献 | |
| 参考文献 |
| 研究领域 | |
| 研究领域 | MetabolismTypes of disease Drug DiscoverySmall Molecule DrugLead Compound Discovery |
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