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| 品牌 | absin | CAS | 123-99-9 |
|---|---|---|---|
| 分子式 | C9H16O4 | 纯度 | ＞98% |
| 分子量 | 188.22 | 货号 | abs47027394 |
| 规格 | 50mg | 供货周期 | 现货 |
| 主要用途 | is a saturated dicarboxylic acid | 应用领域 | 化工,生物产业,农林牧渔,制药/生物制药,综合 |
Azelaic acid 123-99-9
| 产品描述 | |
| 描述 | Azelaic acid is a saturated dicarboxylic acid found naturally in wheat, rye, and barley. It is a natural substance that is produced by Malassezia furfur (also known as Pityrosporum ovale), a yeast that lives on normal skin. It is effective against a number of skin conditions, such as mild to moderate acne, when applied topically in a cream formulation of 20%. It works in part by stopping the growth of skin bacteria that cause acne, and by keeping skin pores clear. Azelaic acid's antimicrobial action may be attributable to inhibition of microbial cellular protein synthesis. |
| 纯度 | ＞98% |
| 储存/保存方法 | Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution. |
| 基本信息 | |
| 别名 | 壬二酸；Nonanedioic acid |
| 外观 | 白色粉末 |
| 可溶性/溶解性 | DMSO : 35 mg/mL (186 mM) Ethanol : 35 mg/mL (186 mM) Water : 34 mg/mL (180.6 mM) |
| 生物活性 | |
| In vitro(体外研究) | AZ(Azelaic acid) combined with taurine (Tau) show more inhibitory effects in melanocytes than the treatment of AZ alone. AZ combined with Tau inhibits the melanin production and tyrosinase activity of B16F10 melanoma cells without significant cytotoxicity. Also inhibitory effects after treatment with these combined chemical are stronger than AZ alone on melanogenesis. |
| In vivo(体内研究) | Azelaic acid exhibits an anti-atherogenic effect. Its athero-protective effect is not related to changes in plasma lipid content. Azelaic acid supplementation decreases the level of CD68 macrophage marker by 34% (p. |
| 参考文献 | |
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| 研究领域 | |
| 研究领域 | Immunology Drug DiscoverySmall Molecule DrugLead Compound Discovery |
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