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CID755673 521937-07-5 CID755673 is a potent and selective cell-active small molecule inhibitor for PKD with an IC50 of 182 nM
C646 328968-36-1 C646 is an inhibitor for histone acetyltransferase, and inhibits p300 with a Ki of 400 nM in a cell-free assay. Preferentially selective for p300 versus other acetyltransferases.
CH 223191 301326-22-7 CH 223191 is a potent and specific aryl hydrocarbon receptor (AhR) antagonist with IC50 of 30 nM.
PD184352 (CI-1040) 212631-79-3 PD184352 (CI-1040) is an ATP non-competitive MEK1/2 inhibitor with IC50 of 17 nM in cell-based assays, 100-fold more selective for MEK1/2 than MEK5. Phase 2.
IC261 186611-52-9 IC261 is a novel inhibitor of CK1, triggers the mitotic checkpoint control. The IC50 of IC261 for CK1 was 16 μM and for Cdk5 is 4.5 mM.
HMN-214 173529-46-9 HMN-214(IVX214) is a potent PLK1 inhibitor an average IC50 of 0.12 μM.
LY 303511 154447-38-8 LY303511, an inactive analogue of LY294002, is a mTOR inhibitor that did not inhibit PI3-K.
PHOB 1429651-50-2 HPOB is a potent, selective HDAC6 inhibitor with IC50 of 56 nM, 30-fold selectivity over other HDACs.
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