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JNK-IN-8 1410880-22-6 JNK-IN-8 is a potent and irreversible JNK inhibitor that inhibits the phosphorylation of c-Jun.
CX-5461 1138549-36-6 CX-5461 is an inhibitor of rRNA synthesis, selectively inhibits Pol I-driven transcription of rRNA, has no effect on Pol II
GSK-923295 1088965-37-0 GSK923295 is a first-in-class, specific allosteric inhibitor of CENP-E kinesin motor ATPase with Ki of 3.2 nM, and less potent to mutant I182 and T183. Phase 1.
wp1066(STAT Inhibitor III) 857064-38-1 WP1066 is a cell-permeable inhibitor of STAT3 that directs dephosphorylation and nuclear export of constitutively phosphorylated STAT.
Bindarit 130641-38-2 Bindarit exhibits selective inhibition against monocyte chemotactic proteins MCP-1/CCL2, MCP-3/CCL7 and MCP-2/CCL8.
CEP-32496 1188910-76-0 Agerafenib is a highly potent inhibitor of BRAF(V600E/WT) and c-Raf with Kd of 14 nM/36 nM and 39 nM, also potent to Abl-1, c-Kit, Ret, PDGFRβ and VEGFR2
KU-60019 925701-49-1；925701-46-8 KU-60019 is an improved analogue of KU-55933, with IC50 of 6.3 nM for ATM.
Evofosfamide(TH-302) 918633-87-1 TH-302 is selective hypoxia-activated prodrug targeting hypoxic regions of solid tumors with IC50 of 19 nM
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