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| 品牌 | absin | 货号 | abs42236361 |
|---|---|---|---|
| 规格 | 10mg;50mg | 供货周期 | 现货 |
| 主要用途 | A selective leukocyte elastase inhibitor |
西维来司钠 150374-95-1
| 产品描述 | |
| 描述 | Sivelestat sodium salt is a selective leukocyte elastase inhibitor (IC50 = 44 nM). Through in vitro observations, Sivelestat functions by blocking LTB4-induced neutrophil transmigration and NF-κB activation. |
| 应用 | A selective leukocyte elastase inhibitor |
| 纯度 | ≥98% |
| 储存/保存方法 | Desiccate at room temperature |
| 形态 | Solid |
| 基本信息 | |
| 别名 | N-[2-[[[4-(2,2-二甲基-1-氧代丙氧基)苯基]磺酰]氨基]苯甲酰]-(S)-甘氨suan单钠盐;N-[2-[[[4-(2,2-Dimethyl-1-oxopropoxy)phenyl]sulfonyl]amino]benzoyl]-(S)-glycine monosodium salt |
| IC50 | Leukocyte elastase: IC50 = 44 nM; neutrophil elastase: IC50 = 44 nM (human); Leukocyte elastase: IC50 = 19-49 nM (rabbit, rat, hamster and mouse) |
| Ki 数据 | neutrophil elastase: Ki= 0.2 nM (human) |
| 可溶性/溶解性 | Soluble in DMSO (50 mM). |
| MDL | MFCD08461731 |
| PubChem CID | 23664980 |
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