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| 品牌 | absin | CAS | 885434-70-8 |
|---|---|---|---|
| 分子式 | C15H19NO2S | 纯度 | 98% |
| 分子量 | 277.38 | 货号 | abs47028405 |
| 规格 | 10mg | 供货周期 | 现货 |
| 主要用途 | is a potent and selective EPAC2 inhibito | 应用领域 | 化工,生物产业,农林牧渔,制药/生物制药,综合 |
HJC0350 885434-70-8
| 产品描述 | |
| 描述 | HJC0350 is a potent and selective EPAC2 inhibitor with IC50 of 0.3 μM, exhibiting no inhibition on Epac1. |
| 纯度 | 98% |
| 储存/保存方法 | Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution. |
| 基本信息 | |
| 可溶性/溶解性 | DMSO:52 mg/mL warmed (187.46 mM) |
| 生物活性 | |
| 靶点 | EPAC2 |
| In vitro(体外研究) | HJC0350 selectively blocks cAMP-induced EPAC2 activation but do not inhibit cAMP-mediated PKA activation. In HEK293/EPAC2-FL cells, HJC0350 also inhibits 007-AM mediated cellular activation of EPAC2. |
| 参考文献 | |
| 参考文献 |
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| 研究领域 | |
| 研究领域 | Signal TransductionSecond MessengerNucleotide MessengercAMP Signal TransductionSecond MessengerNucleotide MessengercGMP Drug DiscoverySmall Molecule DrugLead Compound Discovery |
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