Dihydromyricetin 27200-12-0

简要描述：Dihydromyricetin 27200-12-0
Dihydromyricetin (Ampelopsin, Ampeloptin) is a natural antioxidant flavonoid from Ampelopsis grossedentata.

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品牌	absin	CAS	27200-12-0
分子式	C15H12O8	纯度	＞98%
分子量	320.25	货号	abs47028205
规格	10mg	供货周期	现货
主要用途	is a natural antioxidant flavonoid	应用领域	化工,生物产业,农林牧渔,制药/生物制药,综合

Dihydromyricetin 27200-12-0

产品描述
描述	Dihydromyricetin (Ampelopsin, Ampeloptin) is a natural antioxidant flavonoid from Ampelopsis grossedentata.
纯度	＞98%
储存/保存方法	Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
基本信息
别名	二氢杨梅素；Ampelopsin；Ampeloptin
外观	white to beige powder
可溶性/溶解性	DMSO : ≥ 100 mg/mL (312.26 mM)
生物活性
靶点	GABAA receptor
In vitro(体外研究)	Dihydromyricetin shows antioxidant activity as an effective scavenger of 1,1-diphenyl-2-picrylhydrazyl radical (DPPH). It also inhibits the increase of lipid peroxidation (LPO) values in linolei acid system catalyzed by FeSO4-edetic acid. DHM (1 μM) as a novel anti-alcohol intoxication medication antagonizes both acute EtOH-induced potentiation of GABA(A)Rs and EtOH exposure/withdrawal-induced GABA(A)R plasticity and increases in GABA(A)R alpha4 subunit expression in hippocampus and cultured neurons.
In vivo(体内研究)	Dihydromyricetin (1 mg/kg, i.p.) counteracts acute alcohol (EtOH) intoxication, and also withdrawals signs in rats including tolerance, increased anxiety, and seizure susceptibity. LD50: Mice 1.41g/kg (i.p.)

研究领域
研究领域	CancerTumor biomarkers CancerTumor immunology MetabolismTypes of disease Drug DiscoverySmall Molecule DrugLead Compound Discovery

Dihydromyricetin 27200-12-0温馨提示：本产品仅作科研实验使用，不支持临床等研究

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