6-Hydroxyflavone 6665-83-4

简要描述：6-Hydroxyflavone 6665-83-4
6-Hydroxyflavone is a flavone, a type of chemical compound. It is one of the noncompetitive inhibitors of cytochrome P450 2C9.

产品型号：abs47028186
厂商性质：生产厂家
更新时间：2026-01-22
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详细介绍

品牌	absin	CAS	6665-83-4
分子式	C15H10O3	纯度	99%
分子量	238.25	货号	abs47028186
规格	10mg	供货周期	现货
主要用途	is a flavone, a type of chemical compoun	应用领域	化工,生物产业,农林牧渔,制药/生物制药,综合

6-Hydroxyflavone 6665-83-4

产品描述
描述	6-Hydroxyflavone is a flavone, a type of chemical compound. It is one of the noncompetitive inhibitors of cytochrome P450 2C9. It is reported in leaves of Barleria prionitis Linn. (a common Acanthaceae from India).[1] 6-Hydroxyflavone may have a potential as a therapeutic drug capable for the treatment of anxiety-like disorders.
纯度	99%
储存/保存方法	Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
基本信息
别名	6-羟基黄酮
可溶性/溶解性	10 mM in DMSO
生物活性
靶点	GABAA receptor
In vitro(体外研究)	6HF binds to GABAA receptors with moderate affinity.
In vivo(体内研究)	In mice, 6HF exhibits anxiolytic-like effect in the elevated plus-maze test, unaccompanied at anxiolytic doses by the sedative, cognitive impairing, myorelaxant, motor incoordination and anticonvulsant effects commonly associated with classical BZs when tested in the hole-board, step-through passive avoidance, horizontal wire, rotarod, and pentylenetetrazol (PTZ)-induced seizure tests, respectively.
参考文献
参考文献	1. Wang X, et al. PLoS One. 2015 Mar 19;10(3):e0116409. 2. Ren L, et al. Biochem Pharmacol. 2010 May 1;79(9):1337-44.

研究领域
研究领域	Drug DiscoverySmall Molecule DrugLead Compound Discovery

6-Hydroxyflavone 6665-83-4温馨提示：本产品仅作科研实验使用，不支持临床等研究

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6-Hydroxyflavone 6665-83-4

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