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| 品牌 | absin | CAS | 21593-77-1 |
|---|---|---|---|
| 分子式 | C6H11NO2S | 纯度 | 99% |
| 分子量 | 161.22 | 货号 | abs47028153 |
| 规格 | 5mg | 供货周期 | 现货 |
| 主要用途 | is an organic compound | 应用领域 | 化工,生物产业,农林牧渔,制药/生物制药,综合 |
S-allyl-L-cysteine 21593-77-1
| 产品描述 | |
| 描述 | S-Allyl cysteine (SAC) is an organic compound that is a natural constituent of fresh garlic. It is a derivative of the amino acid cysteine in which an allyl group has been added to the sulfur atom. |
| 纯度 | 99% |
| 储存/保存方法 | Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution. |
| 基本信息 | |
| 别名 | S-烯丙基-L-半胱氨suan；S- 烯丙基别半胱氨suan；蒜氨酸 |
| 外观 | 白色至淡黄色粉末 |
| 可溶性/溶解性 | 10 mM in DMSO Water : >5 mM |
| 生物活性 | |
| In vitro(体外研究) | S-Allyl cysteine (SAC) could suppress NF-κB activation and lower nitric oxide (NO) production in interferon-γ-stimulated RAW264.7 cells. SAC is known for its anti-apoptotic and antioxidant effects in a range of types of somatic cells. SAC manifests antioxidant properties for example in the nervous and cardiovascular systems. |
| In vivo(体内研究) | SAC significantly prevents NSAID-induced gastric ulceration by blocking inflammation. The dietary intake of SAC suppresses protein expression of NF-κB, MAPK, and PKC in kidney of diabetic mice, which in turn declines renal activity and mRNA expression of NOS and COX-2, finally lowers the formation of ROS, nitric oxide, IL-6, TNF-α, and PGE2, as well as improves renal functions. Therefore, SAC is potent anti-inflammatory agents against diabetic nephropathy. |
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| 研究领域 | |
| 研究领域 | Immunology Metabolism Neuroscience Drug DiscoverySmall Molecule DrugLead Compound Discovery |
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