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| 品牌 | absin | CAS | 120638-55-3 |
|---|---|---|---|
| 分子式 | C15H11BrNNaO3.1.5H2O | 纯度 | 95% |
| 分子量 | 383.17 | 货号 | abs47028034 |
| 规格 | 5mg | 供货周期 | 现货 |
| 主要用途 | is the sodium salt form of bromfenac | 应用领域 | 化工,生物产业,农林牧渔,制药/生物制药,综合 |
Bromfenac sodium hydrate 120638-55-3
| 产品描述 | |
| 描述 | Bromfenac Sodium is the sodium salt form of bromfenac, a nonsteroidal anti-inflammatory drug (NSAID) with analgesic and anti-inflammatory activities. Upon ophthalmic administration, bromfenac binds to and inhibits the activity of cyclooxygenase II (COX II), an enzyme which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins (PG). By inhibiting PG formation, bromfenac is able to inhibit PG-induced inflammation, thereby preventing vasodilation, leukocytosis, disruption of the blood-aqueous humor barrier, an increase in vascular permeability and an increase in intraocular pressure (IOP). |
| 纯度 | 95% |
| 储存/保存方法 | Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution. |
| 基本信息 | |
| 别名 | 溴芬酸na水合物；Bromfenac monosodium salt sesquihydrate |
| 外观 | 黄色或橙黄色结晶性粉末 |
| 可溶性/溶解性 | DMSO : ≥ 36 mg/mL (93.95 mM) |
| 生物活性 | |
| 靶点 | COX-2 |
| 参考文献 | |
| 参考文献 |
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| 研究领域 | |
| 研究领域 | Immunology MetabolismTypes of disease Drug DiscoverySmall Molecule DrugLead Compound Discovery |
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