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简要描述：Cevimeline hydrochloride hemihydrate 153504-70-2Cevimeline hydrochloride hemihydrate, a novel muscarinic receptor agonist, is a candidate therapeutic drug for xerostomia in Sjogren's syndrome.
产品型号：abs47028023a厂商性质：生产厂家更新时间：2026-01-13访 问 量：706产品分类
Product Category详细介绍
| 品牌 | absin | CAS | 153504-70-2 |
|---|---|---|---|
| 分子式 | C20H38Cl2N2O3S2 | 纯度 | ＞98% |
| 分子量 | 489.55 | 货号 | abs47028023 |
| 规格 | 10mg | 供货周期 | 现货 |
| 主要用途 | is a candidate therapeutic drug | 应用领域 | 化工,生物产业,农林牧渔,制药/生物制药,综合 |
Cevimeline hydrochloride hemihydrate 153504-70-2
| 产品描述 | |
| 描述 | Cevimeline hydrochloride hemihydrate, a novel muscarinic receptor agonist, is a candidate therapeutic drug for xerostomia in Sjogren's syndrome. |
| 纯度 | ＞98% |
| 储存/保存方法 | Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution. |
| 基本信息 | |
| 别名 | 盐酸西维美林半水合物；SNI-2011；AF102B hydrochloride hemihydrate |
| 外观 | white to tan powder |
| 可溶性/溶解性 | H2O : ≥ 50 mg/mL (204.27 mM) |
| 生物活性 | |
| In vitro(体外研究) | In digested parotid cells, Cevimeline (0.1-100 μM) increases the intracellular Ca2+ concentration. |
| In vivo(体内研究) | Cevimeline (0.008-0.016 mg/kg; intraperitoneal injection; male Wistar rats) treatment shows slowly increasing and lasting salivation, and increased blood flow increment in the parotid gland and pressor response. Cevimeline inhibits angiotensin II-induced water intake and neuronal activity in the subfornical organ at 0.016 mg/kg. |
| 研究领域 | |
| 研究领域 | Neuroscience Drug DiscoverySmall Molecule DrugLead Compound Discovery |
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