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| 品牌 | absin | CAS | 6893-02-3 |
|---|---|---|---|
| 分子式 | C15H12I3NO4 | 纯度 | ＞98% |
| 分子量 | 650.97 | 货号 | abs47027804 |
| 规格 | 10mg | 供货周期 | 现货 |
| 主要用途 | used by the tissues is mainly T3. | 应用领域 | 化工,生物产业,农林牧渔,制药/生物制药,综合 |
3,3',5-Triiodo-L-thyronine 6893-02-3
| 产品描述 | |
| 描述 | Liothyronine is a T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3. |
| 纯度 | ＞98% |
| 储存/保存方法 | Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution. |
| 基本信息 | |
| 别名 | 三碘甲状腺原氨酸；碘噻罗宁；甲碘安; T3；L-3,3',5-Triiodothyronine；Liothyronine；Tresitope |
| 外观 | Off-white to pale yellow powder |
| 可溶性/溶解性 | DMSO : 50 mg/mL (76.81 mM; Need ultrasonic) |
| 生物活性 | |
| 靶点 | TRα,TRβ |
| In vitro(体外研究) | Triiodothyronine (0.01-0.1 μM) results in a decrease in the TRalpha1:TRalpha2 mRNA ratio in HepG2 cells. High liothyronine levels induces a low TRalpha1:TRalpha2 ratio which can protect the cell from excessive triiodothyronine-induced gene expression. |
| 研究领域 | |
| 研究领域 | CancerCancer Metabolism CancerTumor biomarkers NeuroscienceEndocrine system Drug DiscoverySmall Molecule DrugLead Compound Discovery |
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