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| 品牌 | absin | CAS | 10212-25-6 |
|---|---|---|---|
| 分子式 | C9H12ClN3O4 | 纯度 | 98% |
| 分子量 | 261.66 | 货号 | abs47027772 |
| 规格 | 50mg | 供货周期 | 现货 |
| 主要用途 | used mainly in the treatment of leukemia | 应用领域 | 化工,生物产业,农林牧渔,制药/生物制药,综合 |
Ancitabine hydrochloride 10212-25-6
| 产品描述 | |
| 描述 | Cyclocytidine is the prodrug of cytarabine, which is a pyrimidine nucleoside analog that inhibits the DNA synthesis and used mainly in the treatment of leukemia. |
| 纯度 | 98% |
| 储存/保存方法 | Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution. |
| 基本信息 | |
| 别名 | 盐酸环胞苷；Cyclocytidine hydrochloride； Cyclo-CMP hydrochloride；Cyclo-C |
| 外观 | 白色结晶性粉末 |
| 可溶性/溶解性 | DMSO : 10 mg/mL (38.22 mM) Water : 40 mg/mL (152.9 mM) |
| 生物活性 | |
| In vitro(体外研究) | Cyclocytidine HCl (Ancitabine) is the prodrug of cytarabine, which is structurally similar to human deoxycytidine to be incorporated into human DNA and then kills the cell. Cyclocytidine most affects rapidly dividing cells, which require DNA replication for mitosis. Cyclocytidine also inhibits both DNA and RNA polymerases and nucleotide reductase enzymes needed for DNA synthesis. |
| In vivo(体内研究) | Cyclocytidine is a potent immunosuppresant, antiviral and antitumor agent in animals and man, maximum inhibitor effects require the use of complex injection schedules. Cyclocytidine provides treatment for leukemia. |
| 参考文献 | |
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| 研究领域 | |
| 研究领域 | CancerCancer Metabolism Drug DiscoverySmall Molecule DrugLead Compound Discovery |
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