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Midodrine hydrochloride 3092-17-9

简要描述:Midodrine hydrochloride 3092-17-9
Midodrine is converted to its active metabolite, desglymidodrine by deglycination reaction.

  • 产品型号:abs47027763
  • 厂商性质:生产厂家
  • 更新时间:2025-12-29
  • 访  问  量:682

详细介绍

品牌absinCAS3092-17-9
分子式C12H19ClN2O4纯度>98%
分子量290.74货号abs47027763
规格10mg供货周期现货
主要用途is converted to its active metabolite应用领域化工,生物产业,农林牧渔,制药/生物制药,综合

Midodrine hydrochloride 3092-17-9

产品描述
描述

Midodrine is converted to its active metabolite, desglymidodrine by deglycination reaction. Desglymidodrine selectively binds to and activates alpha-1-adrenergic receptors of the arteriolar and venous vasculature. This causes smooth muscle contraction and leads to an elevation of blood pressure. Desglymidodrine diffuses poorly across the blood-brain barrier and is therefore not associated with effects on the central nervous system. Midodrine Hydrochloride is the hydrochloride salt form of midodrine, a direct-acting prodrug and sympathomimetic agent with antihypotensive properties.

纯度
>98%
储存/保存方法
Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution.
基本信息
别名
盐suan米多君
外观
白色结晶性粉末
可溶性/溶解性
10 mM in DMSO
生物活性
靶点
α-adrenergic receptor
参考文献
参考文献
  • 1. Buckner SA, et al. Eur J Pharmacol. 2002 Aug 2;449(1-2):159-65.

  • 2. Taniguchi N, et al. Eur J Pharmacol. 1996 Dec 27;318(1):117-22.

  • 3. Altenbach RJ, et al. J Med Chem. 2004 Jun 3; 47(12):3220-35.

研究领域
研究领域
Drug DiscoverySmall Molecule DrugLead Compound Discovery
Midodrine hydrochloride 3092-17-9温馨提示:本产品仅作科研实验使用,不支持临床等研究

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