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| 品牌 | absin | CAS | 103129-82-4 |
|---|---|---|---|
| 分子式 | C20H25N2O5Cl | 纯度 | 98% |
| 分子量 | 408.88 | 货号 | abs47027751 |
| 规格 | 5mg | 供货周期 | 现货 |
| 主要用途 | is a synthetic dihydropyridine | 应用领域 | 化工,生物产业,农林牧渔,制药/生物制药,综合 |
Levamlodipine 103129-82-4
| 产品描述 | |
| 描述 | Amlodipine is a synthetic dihydropyridine and a calcium channel blocker with antihypertensive and antianginal properties. Amlodipine inhibits the influx of extracellular calcium ions into myocardial and peripheral vascular smooth muscle cells, thereby preventing vascular and myocardial contraction. This results in a dilatation of the main coronary and systemic arteries, decreased myocardial contractility, increased blood flow and oxygen delivery to the myocardial tissue, and decreased total peripheral resistance. This agent may also modulate multi-drug response (MDR) activity through inhibition of the p-glycoprotein efflux pump. |
| 纯度 | 98% |
| 储存/保存方法 | Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution. |
| 基本信息 | |
| 可溶性/溶解性 | 10 mM in DMSO |
| 生物活性 | |
| 靶点 | calcium channel |
| In vitro(体外研究) | Amlodipine is a calcium channel blocker prescribed for the management of angina and hypertension. As a racemic mixture, amlodipine contains (R)- and (S)-amlodipine isomers, but only (S)-amlodipine as the active moiety possesses therapeutic activity. |
| 参考文献 | |
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| 研究领域 | |
| 研究领域 | Drug DiscoverySmall Molecule DrugLead Compound Discovery |
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