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| 品牌 | absin | CAS | 1229-29-4 |
|---|---|---|---|
| 分子式 | C19H22ClNO | 纯度 | 99% |
| 分子量 | 315.84 | 货号 | abs47027747 |
| 规格 | 1g | 供货周期 | 现货 |
| 主要用途 | is a dibenzoxepin tricyclic compound | 应用领域 | 化工,生物产业,农林牧渔,制药/生物制药,综合 |
Doxepin Hydrochloride 1229-29-4
| 产品描述 | |
| 描述 | Doxepin Hydrochloride is a dibenzoxepin tricyclic compound. It displays a range of pharmacological actions including maintaining adrenergic innervation. Its mechanism of action is not fully understood, but it appears to block reuptake of monoaminergic neurotransmitters into presynaptic terminals. It also possesses anticholinergic activity and modulates antagonism of histamine H(1)- and H(2)-receptors. |
| 纯度 | 99% |
| 储存/保存方法 | Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution. |
| 基本信息 | |
| 别名 | 盐酸duo塞平 |
| 外观 | 白色粉末 |
| 可溶性/溶解性 | DMSO : ≥ 100 mg/mL (316.62 mM) H2O : ≥ 50 mg/mL (158.31 mM) |
| 生物活性 | |
| 靶点 | Serotonin Transporter |
| In vitro(体外研究) | Doxepin inhibits the reuptake of serotonin and norepinephrine. Its actions of the reuptake of dopamine are negligible. Doxepin also has antagonistic effects at a variety of receptors including receptors of H1, H2, 5-HT1, 5-HT2, α1-adrenergic and mACh. |
| 参考文献 | |
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| 研究领域 | |
| 研究领域 | CancerCancer Metabolism CancerTumor immunology Drug DiscoverySmall Molecule DrugLead Compound Discovery |
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