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Cisatracurium besylate 96946-42-8

简要描述:Cisatracurium besylate 96946-42-8
Cisatracurium Besylate is a nondepolarizing skeletal muscle relaxant for intravenous administration.

  • 产品型号:abs47027707
  • 厂商性质:生产厂家
  • 更新时间:2025-12-25
  • 访  问  量:622

详细介绍

品牌absinCAS96946-42-8
分子式C53H72N2O12.2C6H5O3S纯度>98%
分子量1243.48货号abs47027707
规格5mg供货周期现货
主要用途is a nondepolarizing skeletal muscle rel应用领域化工,生物产业,农林牧渔,制药/生物制药,综合

Cisatracurium besylate  96946-42-8

产品描述
描述

Cisatracurium Besylate is a nondepolarizing skeletal muscle relaxant for intravenous administration. Cisatracurium Besylate acts on cholinergic receptors, blocking neuromuscular transmission. This action is antagonized by acetylcholinesterase inhibitors such as neostigmine. The neuromuscular block produced by cisatracurium besylate is readily antagonized by anticholinesterase agents once recovery has started. As with other nondepolarizing neuromuscular blocking agents, the more profound the neuromuscular block at the time of reversal, the longer the time required for recovery of neuromuscular function. Compared to other neuromuscular blocking agents, it is intermediate in its onset and duration of action.

纯度
>98%
储存/保存方法
Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution.
基本信息
别名
顺ben磺阿曲库铵;51W89
外观
白色至淡黄色粉末
可溶性/溶解性
DMSO : 229 mg/mL (184.2 mM)

Ethanol : 229 mg/mL (184.2 mM)

Water : 43 mg/mL (34.6 mM)
生物活性
靶点
AChR, Adrenergic Receptor
In vitro(体外研究)
Cisatracurium Besylate (51W89) is a neuromuscular-blocking drug or skeletal muscle relaxant in the category of non-depolarizing neuromuscular-blocking drugs, used adjunctively in anesthesia to facilitate endotracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation. It is a bisbenzyltetrahydroisoquinolinium agent with an intermediate duration of action. Cisatracurium Besylate (51W89) is one of the ten isomers of the parent molecule, atracurium. Moreover, cisatracurium represents approximately 15% of the atracurium mixture.
参考文献
参考文献
  • 1. Dieye E, et al. Ann Intensive Care. 2014 Feb 11;4(1):3.

  • 2. Szakmany T, Woodhouse T. Minerva Anestesiol. 2015 Apr; 81(4):450-60.

  • 3. Dahaba AA, et al. Minerva Anestesiol. 2013 Nov; 79(11):1238-47.

研究领域
研究领域
Neuroscience
CancerCancer Metabolism
Drug DiscoverySmall Molecule DrugLead Compound Discovery
Cisatracurium besylate  96946-42-8温馨提示:本产品仅作科研实验使用,不支持临床等研究

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