Fenofibrate 49562-28-9

简要描述：Fenofibrate 49562-28-9
Fenofibrate is a Peroxisome Proliferator Receptor alpha Agonist.

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详细介绍

品牌	absin	CAS	49562-28-9
分子式	C20H21ClO4	纯度	98%
分子量	360.83	货号	abs47027522
规格	100mg	供货周期	现货
主要用途	is a Peroxisome Proliferator Receptor al	应用领域	化工,生物产业,农林牧渔,制药/生物制药,综合

Fenofibrate 49562-28-9

产品描述
描述	Fenofibrate is a Peroxisome Proliferator Receptor alpha Agonist. The mechanism of action of fenofibrate is as a Peroxisome Proliferator-activated Receptor alpha Agonist. The chemical classification of fenofibrate is PPAR alpha.
纯度	98%
储存/保存方法	Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
基本信息
别名	fei诺贝特
外观	白色或类白色结晶性粉末
可溶性/溶解性	DMSO : 36.1 mg/mL (100 mM) Ethanol : 36.1 mg/mL (100 mM)
生物活性
靶点	Cytochrome P450
In vivo(体内研究)	Daily intake of Fenofibrate at this low dose (10 μg/g/day) inhibits retinal and choroidal neovascularization induced by CYP2C8 overexpression by 29% (P=0.021) and 36% (P=1.2×10−9) respectively.
参考文献
参考文献	1. Clavey V, et al. Cell Physiol Biochem. 1999;9(3):139-49. 2. Walsky RL, et al. J Clin Pharmacol. 2005 Jan;45(1):68-78. 3. Casas F, et al. FEBS Lett. 2000 Sep 29;482(1-2):71-4. 4. Bouly M, et al. J Biol Chem. 2001 Jul 13;276(28):25841-7.

研究领域

CardiovascularLipids / LipoproteinsLipid MetabolismCytochromes

MetabolismPathways and ProcessesMetabolic signaling pathwaysDrug metabolism

MetabolismPathways and ProcessesMetabolic signaling pathwaysLipid and lipoprotein metabolismLipases

MetabolismPathways and ProcessesMitochondrial MetabolismCytochromes

NeuroscienceDevelopment

NeuroscienceProcesses

Signal TransductionMetabolismDrug metabolism

Drug DiscoverySmall Molecule DrugLead Compound Discovery

Fenofibrate 49562-28-9温馨提示：本产品仅作科研实验使用，不支持临床等研究

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