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| 品牌 | absin | CAS | 15686-71-2 |
|---|---|---|---|
| 分子式 | C16H17N3O4S | 纯度 | ＞98% |
| 分子量 | 347.39 | 货号 | abs47027448 |
| 规格 | 50mg | 供货周期 | 现货 |
| 主要用途 | is a synthetic glucocorticoid | 应用领域 | 化工,生物产业,农林牧渔,制药/生物制药,综合 |
Cephalexin 15686-71-2
| 产品描述 | |
| 描述 | Prednisone is a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. |
| 纯度 | ＞98% |
| 储存/保存方法 | Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution. |
| 基本信息 | |
| 别名 | tou孢氨苄；Cefalexin；Cephacillin |
| 外观 | 白色或微黄色结晶性粉末 |
| 可溶性/溶解性 | DMSO : 2 mg/mL (5.75 mM) Water ：10 mg/mL (28.78 mM) |
| 生物活性 | |
| In vitro(体外研究) | Cephalexin uptake by human MATE1-expressing human embryonic kidney 293 cells exhibits saturable kinetics with K(m) = 5.9 mM and a bell-shaped pH profile with a maximum at pH 7.0. Cephalexin results in overestimation of glucose concentration, but only in the samples that contain the highest antimicrobial concentration (2,400microg/mL) and only for the tablet. Cephalexin increases the activity of superficial mucous cells and orifice mucous cells of gastric glands, and inhibits the activity of cervix mucous cells. |
| In vivo(体内研究) | Cephalexin causes a slight prolongation of 1-stage prothrombin time (PT) and activated partial thromboplastin time (PTT) and slight decrease in fibrinogen concentration in healthy dogs. Cephalexin causes a significant increase in 1-stage PT and activated PTT, amoxicillin causes a significant increase in activated PTT, and enrofloxacin causes a significant decrease in fibrinogen concentration. Cephalexin results in high numbers of E. coli producing plasmid-mediated CMY-2 β-lactamase at the end of the treatment period in dogs. |
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| 研究领域 | |
| 研究领域 | MetabolismTypes of disease Drug DiscoverySmall Molecule DrugLead Compound Discovery |
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