Homotaurine 3687-18-1

简要描述：Homotaurine 3687-18-1
Because of its similarity in structure to the neurotransmitter gamma-aminobutyric acid (GABA), it has GABAergic effects and may be useful as an anticonvulsant.

产品型号：abs47027365
厂商性质：生产厂家
更新时间：2025-12-09
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生化试剂

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详细介绍

品牌	absin	CAS	3687-18-1
分子式	C3H9NO3S	纯度	＞98%
分子量	139.17	货号	abs47027365
规格	50mg	供货周期	现货
主要用途	as an anticonvulsant	应用领域	化工,生物产业,农林牧渔,制药/生物制药,综合

Homotaurine 3687-18-1

产品描述
描述	Because of its similarity in structure to the neurotransmitter gamma-aminobutyric acid (GABA), it has GABAergic effects and may be useful as an anticonvulsant. Homotaurine has also been investigated as a potential treatment for Alzheimer's disease. It binds to soluble amyloid beta and inhibits the formation of neurotoxic aggregates that lead to amyloid plaque deposition in the brain. However, clinical trials failed to show improvement compared to placebo.
纯度	＞98%
储存/保存方法	Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
基本信息
别名	3-氨基丙烷磺酸； Homotaurine；3-Amino-1-propanesulfonic acid
外观	白色结晶性粉末
可溶性/溶解性	H2O : 20 mg/mL (143.71 mM; Need ultrasonic) DMSO : 1 mg/mL (7.19 mM; Need ultrasonic)
生物活性
靶点	Amyloid-(beta)
参考文献
参考文献	1. Fariello RG, et al. Neurology, 1982, 32 (3): 241–5. 2. Fariello RG, et al. Neurology, 1982, 32 (3): 241–6. 3. Gauthier, S, et al. The journal of nutrition, health & aging, 2009, 13 (6): 550–7. 4. Gauthier, S, et al. The journal of nutrition, health & aging, 2009, 13 (6): 550–8. 5. Aisen PS, et al. Curr Alzheimer Res, 2007, 4 (4): 473–8.

研究领域
研究领域	CancerCancer Metabolism Drug DiscoverySmall Molecule DrugLead Compound Discovery

Homotaurine 3687-18-1温馨提示：本产品仅作科研实验使用，不支持临床等研究

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