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| 品牌 | absin | CAS | 60940-34-3 |
|---|---|---|---|
| 分子式 | C13H9NOSe | 纯度 | ＞98% |
| 分子量 | 274.18 | 货号 | abs47027330 |
| 规格 | 5mg | 供货周期 | 现货 |
| 主要用途 | is a organoselenium | 应用领域 | 化工,生物产业,农林牧渔,制药/生物制药,综合 |
Ebselen 60940-34-3
| 产品描述 | |
| 描述 | Ebselen is a organoselenium compound with anti-inflammatory, anti-oxidant and cytoprotective activity. Ebselen acts as a glutathione peroxidase mimetic and is thereby able to prevent cellular damage induced by reactive oxygen species (ROS). In addition, this agent inhibits the activity of a variety of enzymes including nitric oxide synthase (NOS), 5-lipoxygenase, cyclooxygenase, protein kinase C (PKC), NADPH oxidase and gastric H+/K+-ATPase. Furthermore, ebselen may be neuroprotective due to its ability to neutralize free radicals upon NMDA receptor activation thus, reducing lipoperoxidation mediated by glutamate-induced excitotoxicity. |
| 纯度 | ＞98% |
| 储存/保存方法 | Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution. |
| 基本信息 | |
| 别名 | 依布硒；SPI-1005； PZ-51； CCG-39161 |
| 外观 | Yellow to beige Crystalline Powder |
| 可溶性/溶解性 | DMSO : 50 mg/mL (182.36 mM） |
| 生物活性 | |
| 靶点 | COX |
| 参考文献 | |
| 参考文献 |
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| 研究领域 | |
| 研究领域 | Immunology Neuroscience CancerTumor immunology MetabolismTypes of disease Drug DiscoverySmall Molecule DrugLead Compound Discovery |
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