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| 品牌 | absin | CAS | 154-23-4 |
|---|---|---|---|
| 分子式 | C15H14O6 | 纯度 | ＞98% |
| 分子量 | 290.27 | 货号 | abs47027327 |
| 规格 | 10mg | 供货周期 | 现货 |
| 主要用途 | is a flavan-3-ol, | 应用领域 | 化工,生物产业,农林牧渔,制药/生物制药,综合 |
Cianidanol 154-23-4
| 产品描述 | |
| 描述 | Catechin((+)-Catechin; D-Catechin) is a flavan-3-ol, a type of natural phenol and antioxidant. |
| 纯度 | ＞98% |
| 储存/保存方法 | Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution. |
| 基本信息 | |
| 可溶性/溶解性 | DMSO 58mg/ml(199.81 mM) Water 58mg/ml(199.81 mM) |
| 生物活性 | |
| 靶点 | COX-1 ,COX-2 |
| In vitro(体外研究) | The catechin flavonoid reduces proliferation and induces apoptosis of murine lymphoma cells LB02 through modulation of antiapoptotic proteins. Treatment of human prostate cancer cells with catechin induces apoptosis and results in effects on a variety of survival signals suggesting the potential of these compounds as chemopreventive agents for prostate cancer. Catechin is well known to inhibit cyclooxygenase activity with reported IC50 values ranging from 4O μM to 943 μM. It has also been reported to act as an inhibitor of COX-1 and COX-2 with IC50 of about 80 µM and 130 μM. |
| In vivo(体内研究) | Dietary catechin significantly delayed tumor onset. Continued intake of catechin, a potential antioxidant, prevents memory regression and DNA oxidative damage in senescence-accelerated (SAMP10) mice. It does not prolong the lifetime of SAMP10 mice, but it does delay brain senescence. (+)-Catechin inhibits intestinal tumor formation and suppresses Focal adhesion kinase activation in the Min/+ Mouse. |
| 参考文献 | |
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| 研究领域 | |
| 研究领域 | CancerTumor immunology Drug DiscoverySmall Molecule DrugLead Compound Discovery |
Cianidanol 154-23-4
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