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| 品牌 | absin | CAS | 770-05-8 |
|---|---|---|---|
| 分子式 | C8H12CINO2 | 纯度 | 99% |
| 分子量 | 189.64 | 货号 | abs47027083 |
| 规格 | 500mg | 供货周期 | 现货 |
| 主要用途 | acts as a neurohormone | 应用领域 | 化工,生物产业,农林牧渔,制药/生物制药,综合 |
Octopamine hydrochloride 770-05-8
| 产品描述 | |
| 描述 | Octopamine (OA), a biogenic monoamine structurally related to noradrenaline, acts as a neurohormone, a neuromodulator and a neurotransmitter in invertebrates. |
| 纯度 | 99% |
| 储存/保存方法 | Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution. |
| 基本信息 | |
| 别名 | 章胺盐酸盐; (+,-)-Octopamine HCl；(±)-p-Octopamine hydrochlorid |
| 外观 | white or off-white solid |
| 可溶性/溶解性 | DMSO : ≥ 100 mg/mL (527.31 mM) water : ≥ 50 mg/mL (263.66 mM) |
| 生物活性 | |
| In vitro(体外研究) | Octopamine is present in relatively high concentrations in neuronal as well as in non-neuronal tissues of most invertebrate species studied, and modulates almost every physiological process. Octopamine acts as neurohormone including desensitization of sensory inputs, influence on learning and memory, or regulation of the mood of the animal in the central nervous system. Octopamine is the only neuroactive non-peptide transmitter whose physiological role is restricted to invertebrates, and all octopamine receptors belong to the family of G-protein coupled receptors. |
| In vivo(体内研究) | Octopamine (10 mg/mL) is necessary for the acquisition of sugar memory in Drosophila. Octopamine treatment increases responsiveness to brood pheromone and decreased responsiveness to social inhibition. Octopamine acts as an important source of variation in response thresholds and as a modulator of pheromonal communication in insect societies. Octopamine (10 μM) injected into the mushroom body (MB) calyces or the antennal lobe but not the lateral protocerebral lobe produces a lasting, pairing-specific enhancement of extension of the proboscis. Octopamine (10 μM) injected into the MB calyces results in an additional pairing-specific effect, because it does not lead to an acquisition but a consolidation after conditioning. Octopamine treatment significantly elevates levels of octopamine in the brain and caused a significant dose-dependent increase in the number of new foragers. Octopamine treatment is effective only when given to bees old enough to forage, i.e., older than 4 days of age. Octopamine influences division of labor in honey bee colonies. |
| 参考文献 | |
| 参考文献 |
| 研究领域 | |
| 研究领域 | Neuroscience NeuroscienceEndocrine system Drug DiscoverySmall Molecule DrugLead Compound Discovery |
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