全国服务咨询热线:

15502157206

Products产品中心
首页 > 产品中心 > 抗体 > 二抗 > abs132700Rabbit anti-CD63 Polyclonal Antibody

Rabbit anti-CD63 Polyclonal Antibody

简要描述:Rabbit anti-CD63 Polyclonal Antibody存储溶液
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

  • 产品型号:abs132700
  • 厂商性质:生产厂家
  • 更新时间:2021-12-19
  • 访  问  量:64

相关文章

Related Articles

详细介绍

品牌自营品牌供货周期现货
应用领域化工,生物产业,能源
概述
描述
This antigen is associated with early stages of melanoma tumor progression. May play a role in growth regulation
别名
CD63抗体;Lysosomal associated membrane protein 3; CD 63; CD63; CD63 antigen (melanoma 1 antigen); CD63 antigen; CD63 antigen melanoma 1 antigen; CD63 molecule; CD63_HUMAN; gp55; Granulophysin; LAMP 3; LAMP-3; LAMP3; LIMP; Lysosomal-associated membrane protein 3; Lysosome associated membrane glycoprotein 3; Mast cell antigen AD1; ME491; Melanoma 1 antigen; Melanoma associated antigen ME491; Melanoma associated antigen MLA1; Melanoma-associated antigen ME491; MGC72893; MLA 1; MLA1; NGA; Ocular melanoma associated antigen; Ocular melanoma-associated antigen; OMA81H; PTLGP40; Tetraspanin 30; Tetraspanin-30; Tspan 30; Tspan-30; TSPAN30;
宿主
Rabbit anti-CD63 Polyclonal Antibody  Rabbit
特异性
CD63 antibody detects endogenous levels of total CD63.
反应种属
Human;Mouse;Rat
应用
WB 1:500-1:2000, IHC 1:50-1:200, IF 1:100-1:500, ELISA(peptide) 1:20000-1:40000
免疫原
A synthesized peptide derived from Human CD63(Accession P08962), corresponding to amino acid residues A148-T174.
性能
浓度
Rabbit anti-CD63 Polyclonal Antibody  1mg/ml
纯化方法
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin .
类型
Polyclonal Antibody
储存/保存方法
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles
存储溶液
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
靶标
背景说明
Functions as cell surface receptor for TIMP1 and plays a role in the activation of cellular signaling cascades. Plays a role in the activation of ITGB1 and integrin signaling, leading to the activation of AKT, FAK/PTK2 and MAP kinases. Promotes cell survival, reorganization of the actin cytoskeleton, cell adhesion, spreading and migration, via its role in the activation of AKT and FAK/PTK2. Plays a role in VEGFA signaling via its role in regulating the internalization of KDR/VEGFR2. Plays a role in intracellular vesicular transport processes, and is required for normal trafficking of the PMEL luminal domain that is essential for the development and maturation of melanocytes. Plays a role in the adhesion of leukocytes onto endothelial cells via its role in the regulation of SELP trafficking. May play a role in mast cell degranulation in response to Ms4a2/FceRI stimulation, but not in mast cell degranulation in response to other stimuli.
组织特异性
Detected in platelets (at protein level). Dysplastic nevi, radial growth phase primary melanomas, hematopoietic cells, tissue macrophages.
翻译后修饰
Palmitoylated at a low, basal level in unstimulated platelets. The level of palmitoylation increases when platelets are activated by thrombin (in vitro).
细胞定位
Endosome;Extracellular region or secreted;Lysosome;Plasma Membrane;
UniProt
P08962
实验结果图
Western blot analysis of CD63 expression in Human platelet lysate;The lane on the left is treated with the antigen-specific peptide.
温馨提示:本产品仅作科研实验使用,不支持临床等研究

产品咨询

留言框

  • 产品:

  • 您的单位:

  • 您的姓名:

  • 联系电话:

  • 常用邮箱:

  • 省份:

  • 详细地址:

  • 补充说明:

  • 验证码:

    请输入计算结果(填写阿拉伯数字),如:三加四=7
爱必信(上海)生物科技有限公司
地址:上海市浦东新区新浩路58号申江科创园18栋
邮箱:zhouzz@absin.cn
传真:
关注我们
欢迎您关注我们的微信公众号了解更多信息:
欢迎您关注我们的微信公众号
了解更多信息
扫一扫访问手机站扫一扫访问手机站
访问手机站