Rabbit anti-CD278/ICOS Recombinant Monoclonal Anti

简要描述：Rabbit anti-CD278/ICOS Recombinant Monoclonal Antibody(R104)，储存溶液：PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300

产品型号：abs171777
厂商性质：生产厂家
更新时间：2025-09-23
访问量：1498

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抗体

药物阳性对照抗体磷酸化抗体二抗病毒抗体标签抗体内参抗体其它一抗

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详细介绍

品牌	absin	CAS	-
分子式	-	纯度	-
分子量	-	货号	abs171777
规格	100uL	供货周期	现货
主要用途	IHC-P: 1:500	应用领域	化工,生物产业,综合

概述
别名	Inducible T-cell costimulator; AILIM
宿主	Rabbit
反应种属	Human
应用	IHC-P: 1:500
性能
形式	Liquid
浓度	0.5 mg/ml
纯化方法	Protein A affinity column
类型	Monoclonal Antibody
克隆号	R104
储存/保存方法	Store at -20℃ for one year.
存储溶液	PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300
靶标
背景说明	Inducible T cell costimulatory factor (ICOS, cluster of differentiation, CD278) is an activated costimulatory immune checkpoint expressed on T cells. Its ligand ICOSL was expressed in antigen-presenting cells and somatic cells (including tumor cells in the tumor microenvironment) [PMID: 28713380, PMID: 12800259]. As one of the most common targeted immune checkpoints, ICOS is considered a possible way to develop new immunotherapy [PMID: 29544515]. Some clinical studies shown that blocking ICOS alone can inhibit tumor growth and proliferation, as well as TIGIT, CTLA4, and PD-1 [PMID: 30232519, PMID: 28803728].
细胞定位	Cell Membrane, Secreted
UniProt	Q9Y6W8
实验结果图
	IHC shows positive staining in paraffin-embedded human thymus. Anti-CD278/ICOS antibody was used at 1/500 dilution, Secondary antibody: #abs20040. Counterstained with hematoxylin. Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.
	IHC shows positive staining in paraffin-embedded human tonsil. Anti-CD278/ICOS antibody was used at 1/500 dilution, Secondary antibody: #abs20040. Counterstained with hematoxylin. Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.
	IHC shows positive staining in paraffin-embedded human tonsil. Anti-CD278/ICOS antibody was used at 1/500 dilution, Secondary antibody: #abs20040. Counterstained with hematoxylin. Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.
	Negative control: IHC shows negative staining in paraffin-embedded human kidney. Anti-CD278/ICOS antibody was used at 1/500 dilution, Secondary antibody: #abs20040. Counterstained with hematoxylin. Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.
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Rabbit anti-CD278/ICOS Recombinant Monoclonal Anti

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