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| 品牌 | absin | CAS | 126784-99-4 |
|---|---|---|---|
| 分子式 | C30H37NO4 | 纯度 | 99% |
| 分子量 | 475.62 | 货号 | abs47028068 |
| 规格 | 5mg | 供货周期 | 现货 |
| 主要用途 | is a novel selective progesterone recept | 应用领域 | 化工,生物产业,农林牧渔,制药/生物制药,综合 |
Ulipristal acetate 126784-99-4
| 产品描述 | |
| 描述 | Ulipristal acetate(CDB2914) is a novel selective progesterone receptor modulator (SPRM) for the treatment of benign gynecological conditions such as uterine myoma. |
| 纯度 | 99% |
| 储存/保存方法 | Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution. |
| 基本信息 | |
| 可溶性/溶解性 | 10 mM in DMSO |
| 生物活性 | |
| 靶点 | Progesterone receptor |
| In vitro(体外研究) | Ulipristal acetate has partial agonistic as well as antagonistic effects on the progesterone receptor. It also binds to theglucocorticoid receptor, but has no relevant affinity to the estrogen, androgen and mineralocorticoid receptors. |
| In vivo(体内研究) | Based on clinical trials, ulipristal acetate seems to be a reasonably tolerable and effective method of emergency contraception when used within 120 hours of intercourse. Ulipristal acetate is at least as effective as LNG when used within the first 72 hours after unprotected intercourse. However, ulipristal acetate may be more effective than LNG when used between 72 to 120 hours after unprotected intercourse, extending the window of opportunity for emergency contraception. |
| 参考文献 | |
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| 研究领域 | |
| 研究领域 | CancerSignal transductionNuclear signalingNuclear hormone receptorsProgesterone CancerTumor biomarkersReceptors EpigeneticsNuclear Signaling PathwaysNuclear ReceptorsProgesterone EpigeneticsTranscriptionDomain FamiliesZinc Finger NeuroscienceDevelopment NeuroscienceProcesses NeuroscienceEndocrine systemGonadotrophic axis Signal TransductionSignaling PathwayNuclear SignalingNuclear Hormone ReceptorsProgesterone Drug DiscoverySmall Molecule DrugLead Compound Discovery |
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