VE-821 1232410-49-9 VE-821 is a potent and selective ATP competitive inhibitor of ATR with Ki and IC50 of 13 nM and 26 nM, respectively.

Ixazomib Citrate 1201902-80-8 MLN-9708 is a proteasome inhibitor, which inhibits the activity of the proteasome, blocking the targeted proteolysis normally performed by the proteasome.

GSK-3787 188591-46-0 GSK3787 is as a potent and selective antagonist of PPARδ with pIC50 of 6.6.

I-BET151 1300031-49-5 I-BET151 (GSK1210151A) is a novel selective BET inhibitor for BRD2, BRD3 and BRD4 with IC50 of 0.5 μM, 0.25 μM, and 0.79 μM, respectively.

Omecamtiv mecarbil (CK-1827452) 873697-71-3 Omecamtivmecarbil (CK-1827452) is a specific cardiac myosinactivator and a clinical drug for left ventricular systolic heart failure.

JNJ26854165 881202-45-5 JNJ-26854165 (Serdemetan) acts as a HDM2 ubiquitin ligase antagonist and also induces early apoptosis in p53 wild-type cells

TAK-632 1228591-30-7 TAK-632 is a selective pan-RAF kinase inhibitor with IC50 values of 2.4/1.4 nM for BRAF V600E/c-RAF; 60 fold selectivity over VEGFR.

SC-514 (GK 01140) 354812-17-2 SC-514 (GK 01140), a small molecule, is a selective inhibitor of IKK-2; does not inhibit other IKK isoforms or other serine-threonine and tyrosine kinases.