E6 Berbamine 73885-53-7

Name: E6 Berbamine 73885-53-7abs42017634
Brand: absin
Price: 1488 CNY
Availability: InStock

简要描述：E6 Berbamine 73885-53-7
A selective and cell-permeable CaM antagonist

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详细介绍

品牌	absin	CAS	73885-53-7
分子式	C44H43N3O9	分子量	757.83
货号	abs42017634	规格	10mg
供货周期	现货	主要用途	A selective and cell-permeable CaM anta
应用领域	化工,生物产业,农林牧渔,制药/生物制药,综合

E6 Berbamine 73885-53-7

产品描述
描述	E6 Berbamine is a potent, selective, cell-permeable CaM (calmodulin) antagonist which inhibits calmodulin-dependent enzymes such as MYLK (myosin light chain kinase) (IC50=8 µM) and PDE (phosphodiesterase I) (IC50=0.53 µM).
应用	A selective and cell-permeable CaM antagonist
使用方法	Store solutions at -20°C for up to 3 months.
储存/保存方法	Store at -20° C
基本信息
别名	6,6',7-Trimethoxy-2,2'-dimethylberbaman-12-yl acetate; Calmodulin inhibitor
密度	1.26 g/cm3
折射率	n20D 1.61
IC50	MLC kinase: IC50 = 8 µM; phosphodiesterase I: IC50 = 0.53 µM; imatinib-resistant K562 leukemia cells expressing p210Bcr/Abl and MDR1 at 48 hrs: IC50 = 2.13 µM (human)
PK值	pKb: 7.69
可溶性/溶解性	Soluble in water (700 mg/L at 25 °C), chloroform (44.51 g/100mL at 25 °C), dichloromethane (19.20 g/100mL at 25 °C), methanol (9.98 g/100mL at 25 °C), DMSO (50 mM), ethanol (1.28 g/100mL at 25 °C)
PubChem CID	6610268

E6 Berbamine 73885-53-7温馨提示：本产品仅作科研实验使用，不支持临床等研究

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