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(+)MK-801 maleate 77086-22-7 Dizocilpine maleate(MK 801) is a potent N-methyl-D-aspartate (NMDA) receptor antagonist with Ki of 30.5 nM
(+)-JQ-1 1268524-70-4 (+)-JQ1 is a BET bromodomain inhibitor, binding to all bromodomains of the BET family, but not to bromodomains outside the BET family.
(+)-Bicuculline 485-49-4 (+)-Bicuculline is an antagonist of the GABAA receptor.
17-AAG 75747-14-7 Tanespimycin (17-AAG)是一种有效的HSP90抑制剂,无细胞试验中IC50为5 nM,作用于来自肿瘤细胞的HSP90比作用于来自正常细胞HSP90结合亲和力高100倍。
Rapamycin 53123-88-9 作用于HEK293细胞,抑制内源性mTOR活性,IC50为~0.1nM,而iRap和AP21967 作用时,IC50分别为~5 nM 和~10 nM。Rapamycin处理酿酒酵母,诱导细胞周期停在G1/S期,且抑制翻译。
Surfactin 24730-31-2 Surfactin is lipopeptide antibiotic. Powerful biosurfactant resulting in the lysis of erythrocytes and bacteria. Also a clotting inhibitor.
Y-27632 146986-50-7 Y-27632 is a selective ROCK1 (p160ROCK) inhibitor with Ki of 140 nM in a cell-free assay, exhibits 200-fold selectivity over Others kinases, including PKC
Y-27632 2HCl 129830-38-2 Y-27632 2HCl is a selective ROCK1 (p160ROCK) inhibitor with Ki of 140 nM.